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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22567 | AMPK activator | Others | |
AMPK activator | |||
T60675L | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK |
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and mi... | |||
T62238 | AMPK activator 4 | AMPK | |
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle tissue and dose-dependently improves glucose tolerance in nor... | |||
T70862 | AMPK Activator SC4 | ||
SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake. | |||
T10069 | AMPK activator 1 | Others | |
AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM). | |||
T78791 | AMPK activator 12 | AMPK | |
AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research. | |||
T23734 | AMPK activator C2 | Compound 2,Compound-2,C2 | |
AMPK activator C2 is an AMPK allosteric activator. | |||
T63177 | AMPK activator 8 | ||
AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to... | |||
T72690 | AMPK activator 9 | ||
AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 µM, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its ... | |||
T83127 | AMPK activator 13 | AMPK | |
AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal expansion in 3T3-L1 cells and enhancing mitochondrial oxygen consumption rates. This compound is utilized in the study of... | |||
T62052 | AMPK activator 6 | ||
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (... | |||
T79226 | AMPK activator 11 | Mitochondrial Metabolism | |
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative... | |||
T63117 | AMPK activator 7 | ||
AMPK activator 7 (compound I-3-24) is an AMPK activator (EC50: 8.8 nM). AMPK activator 7 can be used in studies involving AMPK disorders, particularly type 2 diabetes, hyperglycaemia, metabolic syndrome, obesity, hyperch... | |||
T83125 | AMPK-α1β1γ1 activator 1 | AMPK | |
AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1 isoforms of human AMPK with an EC50 of 38.1 nM through direct bindi... | |||
T60675 | AMPK activator 2 | AMPK | |
AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer ... | |||
T70860 | Banoxantrone | AQ4N | |
Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. ... | |||
T9010 | IMM-H007 | Others , AMPK | |
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression | |||
T16099 | MK8722 | AMPK | |
MK8722 is an effective and systemic activator of pan-AMPK. | |||
T13368 | YLF-466D | C24 | AMPK |
YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation. | |||
TN1731 | Hernandezine | TNF , ROS , P-gp , AMPK | |
Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells. |