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Search Results for " ampk activator "

20

Compounds

Cat No. Product Name Synonyms Targets
T22567 AMPK activator Others
AMPK activator
T60675L AMPK activator 2 hydrochloride( 2410961-69-0 Free base) AMPK activator 2 hydrochloride( 2410961-69-0 Free base) AMPK
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and mi...
T62238 AMPK activator 4 AMPK
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle tissue and dose-dependently improves glucose tolerance in nor...
T70862 AMPK Activator SC4
SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.
T10069 AMPK activator 1 Others
AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).
T78791 AMPK activator 12 AMPK
AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research.
T23734 AMPK activator C2 Compound 2,Compound-2,C2
AMPK activator C2 is an AMPK allosteric activator.
T63177 AMPK activator 8
AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to...
T72690 AMPK activator 9
AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 µM, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its ...
T83127 AMPK activator 13 AMPK
AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal expansion in 3T3-L1 cells and enhancing mitochondrial oxygen consumption rates. This compound is utilized in the study of...
T62052 AMPK activator 6
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (...
T79226 AMPK activator 11 Mitochondrial Metabolism
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...
T63117 AMPK activator 7
AMPK activator 7 (compound I-3-24) is an AMPK activator (EC50: 8.8 nM). AMPK activator 7 can be used in studies involving AMPK disorders, particularly type 2 diabetes, hyperglycaemia, metabolic syndrome, obesity, hyperch...
T83125 AMPK-α1β1γ1 activator 1 AMPK
AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1 isoforms of human AMPK with an EC50 of 38.1 nM through direct bindi...
T60675 AMPK activator 2 AMPK
AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer ...
T70860 Banoxantrone AQ4N
Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. ...
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T16099 MK8722 AMPK
MK8722 is an effective and systemic activator of pan-AMPK.
T13368 YLF-466D C24 AMPK
YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.
TN1731 Hernandezine TNF , ROS , P-gp , AMPK
Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.
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